What Renflexis treats
Renflexis (infliximab-abda) is a biosimilar to Remicade, approved for the treatment of several chronic inflammatory autoimmune conditions. It is used to manage moderate to severe rheumatoid arthritis, Crohn’s disease, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis. Renflexis works by targeting and neutralizing tumor necrosis factor-alpha (TNF-alpha), a key driver of inflammation.
Benefits of Renflexis
Patients using Renflexis often experience:
- Reduced joint pain, stiffness, and swelling
- Fewer gastrointestinal flare-ups in IBD
- Improved skin clearance in psoriasis
- Better physical function and overall quality of life
- Long-term control of autoimmune inflammation
As a biosimilar, Renflexis offers the same safety and efficacy as Remicade, often with potential cost savings.
Possible Side Effects of Renflexis
Common side effects may include:
- Headache
- Nausea
- Upper respiratory infections
- Infusion-related reactions (e.g., chills, fever, rash)
Serious risks, though rare, include:
- Increased susceptibility to infections, including tuberculosis
- Liver abnormalities
- Rare neurological conditions
- Potential for certain malignancies with long-term use
Patients are typically screened for latent infections before starting therapy and monitored regularly during treatment.
How infusion works at Prime
Renflexis is administered at our infusion centers across New York and Atlanta. Our dedicated care team coordinates every step of your treatment with your prescribing physician.
Getting started
Patients: if you have a referral for Renflexis, send us an inquiry using the form below and our care team will take it from there. Physicians: referring a patient to Prime Infusions is simple — just complete and fax or email the referral form above.
Ready to start?
For a medical emergency, call 911.
Our Infusion Centers
FAQ
Frequently asked questions
How Does Renflexis Work?
Renflexis binds to TNF-alpha, a cytokine involved in systemic inflammation. In autoimmune diseases, excessive TNF-alpha causes the immune system to attack healthy tissues, leading to pain, swelling, and tissue damage. By neutralizing TNF-alpha, Renflexis helps to reduce inflammation and prevent further progression of disease. It is administered via intravenous infusion at regular intervals, with dosing tailored to the condition being treated.
Who is Renflexis For?
Renflexis is indicated for adults and children (6 years and older for certain conditions) with:
- Moderate to severe rheumatoid arthritis (with methotrexate)
- Moderate to severe Crohn’s disease
- Moderate to severe ulcerative colitis
- Psoriatic arthritis
- Ankylosing spondylitis
- Chronic severe plaque psoriasis
It is prescribed when other therapies are ineffective or not tolerated.